Belal Firwana, Nazir Ibrahim, Rokana Taftaf, Anas Shaneh Saz, Mohamad Bassam Sonbol, Rim Hasan, Christian Gluud

2011

Cochrane Database of Systematic Reviews

3

John Wiley & Sons, Ltd

Our site uses cookies to improve your experience. You can find out more about our use of cookies in About Cookies, including instructions on how to turn off cookies if you wish to do so. By continuing to browse this site you agree to us using cookies as described in About Cookies … Your language preference is set to English. Where translations are available, article sections will display in this language. Return to English … To evaluate the beneficial and harmful effects of copper‐chelating agents in treating patients with Wilson's disease … Wilson's disease is an autosomal recessive disorder of copper metabolism with a worldwide distribution. The average prevalence of the disease is 30 individuals per million population (Frydman 1990), whereas even higher numbers are observed in areas of consanguinity (Rahil 2010). Wilson's disease is caused by mutations in the ATP7B gene localised on chromosome 13q14.3,6 encoding the ATP7B protein. This protein is …