Authors

Prof. Dr. Yousser Mohammad

Published in

World Journal of Pharmaceutical Research, Vol 7, Issue 12, 2018

Abstract

GOLD Definition of COPD 2018

- common, preventable and treatable disease that is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities usually caused by significant exposure to noxious particles or gases

- In 2016 and before inflammation was included

COPD, a common preventable and treatable disease, is characterized

by persistent airflow limitation that is usually progressive and enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and Comorbidities contribute to the overall severity in individual patients

As you see above, the word inflammation has been deleted from the definition in 2017, the aim was to reduce the use of leS even in combination with long acting bronchodilators (LABA and/ or LAMA) as preventive daily treatment. That was because, follow up studies evidenced pneumonia caused by ICS in COPD patients, and withdrawal syndrome

This was more pronounced when ICS was prescribed alone, and in this case mortality rate is higher

Burden and risk factors

COPD is one of the most common chronic lung diseases, 210 millions in the world suffer of COPD21, and it is projected to be the 3rd cause of mortality in the world by 2020 if risk factors are not avoided

Keywords

Links

www.wjpr.net/download/article/1529306301.pdf