Drug Synthesis
[1st semester, 2018-2019]
Instructor |
Email |
Office Location & Hours |
anasrajab@gmail.com |
[Faculty of Pharmacy, 1-3 pm, Sunday, Tuesday, Wednesday] |
This course aims to provide the student with the following:
1 – The importance, for a medicinal chemist, of having adequate information about chemical groups and their reactions and uses in drug synthesis.
2- Identification synthetic organic compounds by using spectroscopic methods (NMR, MS, IR, UV).
3- How to propose chemical chart for any chemical organic formula to be synthetized starting from lead compound.
4- Synthesizing or semi synthesizing some drugs which have aromatic and hetero aromatic rings
Chemistry for Pharmacy Students; Satyajit D. Sarker, Lutfun Nahar ; john Wiley& sonc, Ltd , 2007 (ورقي ).
|
Week |
Topic |
Reading |
Exercises |
1 |
22/9 – 27/9 |
Introduction |
|
|
2 |
29/9 – 4/10 |
Chemical reactions that are used in medicinal synthesis and the main rules of organic synthesis |
|
|
3 |
6/10 – 11/10 |
Ultraviolet and infrared spectroscopy (IR, UV) |
|
|
4 |
13/10 – 18/10 |
Mass spectrometry and NMR spectroscopy (H1NMR, C13NMR, MS) |
|
|
5 |
20/10 – 25/10 |
Synthesis of Semi-finished materials |
|
|
6 |
27/10 – 1/11 |
study of some general methods in drug synthesis that based on the benzene ring substituted. |
|
|
7 |
3/11 – 8/11 |
Synthesis of nonsteroidal anti-inflammatory drugs (NSAID’s) |
|
|
8 |
10/11 – 15/11 |
study of some general methods in drug synthesis that based on the Rings Heterocyclic |
|
|
9 |
17/11 – 22/11 |
study of some general methods in drug synthesis that based on the Rings Heterocyclic |
|
|
10 |
24/11 – 29/11 |
study of some general methods in drug synthesis of steroid drugs |
|
|
11 |
1/12 -6/12 |
study of some general methods in drug synthesis of antibiotics (Sulfamide compounds) |
|
|
12 |
8/12 – 13/12 |
study of some general methods in drug synthesis of antibiotics (penicillines) |
|
|
13 |
15/12 – 20/12 |
study of some general methods in drug synthesis of antibiotics (penicillin family) |
|
|
14 |
22/12 – 27/12 |
study of some general methods in drug synthesis of antibiotics (cephalosporin family ) |
|
|
15 |
29/12 – 3/1 |
study of some general methods in drug synthesis of drugs sugar |
|
|
test |
Date |
Subject |
Reading |
Type |
language |
% of final grade |
Quizz 1 |
27/10 till 1/11 |
First 6 chapters |
Chapter/pp |
written |
Arabic |
5% |
Quizz 2 |
8/12 till 13/12 |
Last 6 chapters |
Chapter/pp |
written |
Arabic |
5% |
Final |
5/1 till 17/1 |
All chapters |
Chapter/pp |
written |
Arabic |
60% |
Syrian Private University - Pharmacy @ 2024 by Syrian Monster - Web Service Provider | All Rights Reserved