Pharmaceutical Chemistry 1

Pharmaceutical Chemistry 1

( Second Semester 2018/2019 )

Instructor Information

Instructor

Email

Office Location & Hours

Prof. Dr. Adel Nofel

Adel.nofal@gmail.com

Dean office

 

General Information

Description

-    Classification of drugs according to homogenize groups or subgroups so enable the student to deliver the molecular formula , pharmacological actions and uses.

-    Chemical structure, Functional group for drug groups or lead compounds and the synthesis of some drugs.

-    Compendial Physicochemical characteristic, Identification, assay of drugs by applying chemical and instrumental analysis.

-    Pharmacological effects and adverse adverse and daily doses for principal drugs.

-    Studying Structure-Activity relationships of drug group or certain drugs .

Expectations and Goals

1-             enable the student to deliver the molecular formula , pharmacological actions and uses from the above classification.

2-             enable the student to deduct the uses of any drug from the previous knowledge of its pharmacological group.

3-             enable the student to practice the identification .

4-             enable the student to practice the assay.

5-             enable the students to use their theoretical and practical knowledge in drug design and drug syntheses and manufacturing of dosage form. 

Language(s) of Instruction:  Arabic / English                             Textbook(s) Language(s): Arabic / English

Course Materials

Required Text

Reference book in Arabic :

" الكيمياء الصيدلية وتصميم الدواء – تاريخ وتوصيف الأدوية"-  منشورات:  المركز العربي للتعريب والترجمة   

والتاليف والنشر -دمشق -2018 .المؤلف: ا.د عادل نوفل

 

Reference book in Engish : Textbook: Wilson and Gisfold of organic Medicinal Pharmaceutical Chemistry,2017

Course Schedule

 

Week

Topic

Reading

Exercises

1

9/2 – 12/2

Psycholeptic: Hypnotics, Anxiolytics and Antiepleptics - Antipschotics

Power point

Practical section

2

16/2 – 21/2

Psycholeptic: Hypnotics, Anxiolytics and Antiepleptics - Antipschotics

Power point

Practical section

3

23/2 – 28/2

Psychoanaleptics: Tricyclic Antidepressants (Monoamine Reuptacke Inhibitors) Selective Serotonin Reuptacke Inhibitos – Mono-Amino-Oxydase Inhibitors M.A.O.Is

Power point

Practical section

4

2/3 – 7/3

Psychoanaleptics: Tricyclic Antidepressants (Monoamine Reuptacke Inhibitors) Selective Serotonin Reuptacke Inhibitos – Mono-Amino-Oxydase Inhibitors M.A.O.Is

Power point

Practical section

5

9/3 – 14/3

Steroid Hormones: Estrogens-Androgens-Progestins,Progestagenes – Adrenal Cortex Hormones

Power point

Practical section

6

16/3 – 21/3

Steroid Hormones: Estrogens-Androgens-Progestins,Progestagenes – Adrenal Cortex Hormones

Power point

Practical section

7

23/3 – 28/3

Antibiotics and Antimicrobial Agents

Power point

Practical section

8

30/3 – 4/4

Antibiotics and Antimicrobial Agents

Power point

Practical section

9

6/4 – 11/4

Sympathomimetics: Adrenaleine (Epinerphrine) group and analogus,Ephedrine group , Amphetamine and Anorexigenes

Power point

Practical section

10

13/4 – 18/4

Para Sympatholytics: Atropine and other Synthetic Anticholonergics

Power point

Practical section

11

20/4 – 25/4

Antithistaminic and Related Antiallergic and Antiulcer Angents

Power point

Practical section

12

27/4 – 2/5

Analgesic , Antipyretic and non steroidal anti inflammatory

Power point

Practical section

13

4/5 – 9/5

Central analgesics

Power point

Practical section

14

11/5 – 16/5

Anti hyperurcemic

Power point

Practical section

15

18/5 – 23/5

Antiviral drugs

Power point

Practical section

Testing Schedule

test

Date

Subject

Reading

Type

language

% of final grade

Quizz 1

16/3

Psycholeptic

Psychoanaleptics

English

written

English

5%

Quizz 2

27/4

Steroid Hormones

Antibiotics and Antimicrobial Agents

English

written

English

5%

Exam

25/5

All subject

English

MCQ/written

English

60%

General notes:

-       Practical sections 25 %

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