Instructor Information

Instructor	Email	Office Location & Hours
Associ.Prof.Hind El-Zein	dr.hindalzein@gmail.com	[Location, Hours, Days]

General Information

Definition of biopharmacy and pharmacokinetics scienceconcentrating on in vitro/in vivo correlation, learning about bioavailability and bioequivalence studies, and using mathematics equations and compartment models in describing bioprocesses occurring in the body.

Expectations and Goals

1- Learning about in vitro studies for evaluation of pharmaceutical dosage forms

2- …learning about compartments model

3- learning about bioavailability and bioequivalence studies

4- … learning about clinical kinetics.

5- ….dose adjustment according to total and renal clearance.

Language(s) of Instruction: Arabic and English Textbook Language English

Course Materials Arabic and English

1-Applied Biopharmaceutics and Pharmacokinetics,by Leon Chargel, Mac Graw Hill, sixth edition.

2. Clinical pharmacokinetics – Concepts and Applications by Thomas Tozer, Malcolm Rowland.

Course Schedule

	Week	Topic	Reading	Exercises
1	24/9-	Definition of biopharmacy science	Power point	Practical section
2	1/10	Dissolution apparatus and in vitro/in vivo correlation	Power point	Practical section
3	7/10	Comparing dissolution profiles using f1and f2	Power point	Practical section
4	14/10	Biopharmaceutical classification systems	Power point	Practical section
5	21/10	Kinetics of drug after single IV dose	Power point	Practical section
6	28/10	Problems	Power point	Practical section
7	4/11	Kinetics of drug after oral dose	Power point	Practical section
8	11/11	Bioavailability and bioequivalence	Power point	Practical sectionv
9	18/11	Kinetics of drug after IV infusion	Power point	Practical section
10	25/11	Multi compartment model	Power point	Practical section
11	2/11	Renal clearance	Power point	Practical section
12	9/11	Hepatic clearance	Power point	Practical section
13	16/11	Multi doses regime	Power point	Practical section
14	23/11	Dose adjustment according to drug clearnce	Power point	Practical section
15	30/11	Kinetics of protein drug binding	Power point	Practical section

Testing Schedule

test	Date	Subject	Reading	Type	language	% of final grade
Quizz 1	14.10	Dissolution apparatus	English	MCQ/written	Arabic/English	5
Quizz 2	18/11	Kinetics problems	English	MCQ/written	Arabic/English
Final exam	1/2019	all	English	MCQ	Arabic	65

General notes:

- ….