Biopharmacy and Pharmacokinetics

Biopharmacy and Pharmacokinetics
[second semester 2020-2021
Instructor Information
Instructor Email Office Location & Hours
Associ.Prof.Hind El-Zein dr.hindalzein@gmail.com [Location, Hours, Days]
General Information
Definition of biopharmacy and pharmacokinetics scienceconcentrating on in vitro/in vivo correlation, learning about bioavailability and bioequivalence studies, and using mathematics equations and compartment models in describing bioprocesses occurring in the body.

Expectations and Goals

1- Learning about in vitro studies for evaluation of pharmaceutical dosage forms
2- …learning about compartments model
3- learning about bioavailability and bioequivalence studies
4- … learning about clinical kinetics.
5- ….dose adjustment according to total and renal clearance.

Language(s) of Instruction: Arabic and English Textbook Language English
Course Materials Arabic and English
1-Applied Biopharmaceutics and Pharmacokinetics,by Leon Chargel, Mac Graw Hill, sixth edition.
2. Clinical pharmacokinetics – Concepts and Applications by Thomas Tozer, Malcolm Rowland.

Course Schedule
Week Topic Reading Exercises
1 24/9- Definition of biopharmacy science Power point Practical section
2 1/10 Dissolution apparatus and in vitro/in vivo correlation Power point Practical section
3 7/10 Comparing dissolution profiles using f1and f2 Power point Practical section
4 14/10 Biopharmaceutical classification systems Power point Practical section
5 21/10 Kinetics of drug after single IV dose Power point Practical section
6 28/10 Problems Power point Practical section
7 4/11 Kinetics of drug after oral dose Power point Practical section
8 11/11 Bioavailability and bioequivalence Power point Practical sectionv
 

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